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IDT publications

Peer-reviewed articles published by IDT scientists. Filter using one or more categories to focus on specific topics.

169 Citations found

Ramachandran S, Krishnamurthy S, Jacobi AM, Wohlford-Lenane C, Behlke MA, Davidson BL, and McCray PB. (2013) Efficient delivery of RNA-interference oligonucleotides to polarized airway epithelia in vitro. Am J Physiol Lung Cell Mol Physiol, 305 : L23-32.
Lennox KA, Owczarzy R, Thomas DM, Walder JA, and Behlke MA. (2013) Improved performance of anti-miRNA oligonucleotides using a novel non-nucleotide modifier. Molec Ther Nucleic Acids, 2 : e117.
Ramachandran S, Karp PH, Osterhaus SR, Jiang P, Wohlford-Lenane C, Lennox KA, Jacobi AM, Praekh K, Rose SD, Behlke MA, Xing Y, Welsh MJ, McCray PB Jr. (2013) Post-transcriptional regulation of cystic fibrosis transmembrane conductance regulator expression and function by microRNAs. Am J Respir Cell Mol Biol, 49 : 544–551.
Zhang X, Song Y, Shah AY, Lekova V, Raj A, Huang L, Behlke MA, and Tsourkas A. (2013) Quantitative assessment of ratiometric bimolecular beacons as a tool for imaging single engineered RNA transcripts and measuring gene expression in living cells. Nucleic Acids Res, 41 : e152.
Keiser MS, Geoghegan JC, Boudreau RL, Lennox KA, Davidson BL. (2013) RNAi or overexpression: alternative therapies for spinocerebellar ataxia type 1. Nuerobiol Dis, 56 : 6–13.
Dahan L, Huang L, Kedmi R, Behlke MA, and Peer D. (2013) SNP detection in mRNA in living cells using allele specific FRET probes. PLoS ONE, 8 : e72389.
Tetreault P, Beaudet N, Perron A, Belleville K, Rene A, Cavelier F, Martinez J, Stroh T, Jacobi AM, Rose SD, Behlke MA, and Sarret P. (2013) Spinal NTS2 receptor activation reverses signs of neuropathic pain. FASEB J, 27 : 3741-3752.
Fernandez G, Zaikos TD, Khan SZ, Jacobi AM, Behlke MA, Zeichner SL. (2013) Targeting Iκβ proteins for HIV latency activation: the role of individual Iκβ and NF-κβ proteins. J Virol, 87 : 3966–3978.
Goraczniak R, Wall BA, Behlke MA, Lennox KA, Ho ES, Zaphiros NH, Jakubowski C, Patel NR, Zhao S, Magaway C, Subbie SA, Jenny Yu L, Lacava S, Reuhl KR, Chen S, Gunderson SI.. (2013) U1 adaptor oligonucleotides targeting BCL2 and GRM1 suppress growth of human melanoma xenografts in vivo. Mol Ther Nucleic Acids, 14 : e92.
Ramachandran S, Karp PH, Jiang P, Ostedgaard LS, Walz AE, Fisher JT, Keshavjee S, Lennox KA, Jacobi AM, Rose SD, Behlke MA, Welsh MJ, Xing Y, McCray PB Jr. (2012) A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci USA, 109 : 13362–13367.
Gantier MP, Stunden HJ, McCoy CE, Behlke MA, et al. (2012) A miR-19 regulon that controls NF-kB signaling. Nucleic Acids Res, 40 : 8048–8058.
Janas MM, Wang B, Harris AS, Aguiar M, Shaffer JM, Subrahmanyam YV, Behlke MA, Wucherpfennig KW, Gygi SP, Gagnon E, Novina CD. (2012) Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins. RNA, 18 : 2041–2055.
Zhou J, Song M-S, Jacobi AM, Behlke MA, Wu X, Rossi JJ. (2012) Deep sequencing analyses of DsiRNAs reveal the influence of 3’ terminal overhangs on dicing polarity, strand selectivity and RNA editing of siRNAs. Mol Therapy Nucleic Acids, 1 : e17.
Hernandez FJ, Stockdale KR, Huang L, Horswill AR, Behlke MA, McNamara JO. (2012) Degradation of nuclease-stabilized RNA oligonucleotides in mycoplasma-contaminated cell culture media. Nucleic Acid Ther, 22 : 58–68.
Krishnamurthy S, Behlke MA, Ramachandran S, Salem AK,McCray PB Jr, Davidson BL. (2012) Manipulation of cell physiology enables gene silencing in well-differentiated airway epithelia. Mol Ther Nucl Acids, 1 : e41.
Munoz-Alarcon A, Guterstam P, Romero C, Behlke MA, Lennox KA, Wengel J, El Andaloussi S, Langel U. (2012) Modulating anti-microRNA-21 activity and specificity using oligonucleotide derivatives and length optimization. ISRN Pharm, 2012 : e407154.
Kredo-Russo S, Mandelbaum AD, Ness A, Alon I, Lennox KA, Behlke MA, Hornstein E. (2012) Pancreas-enriched miRNA refines endocrine cell differentiation. Development, 139 : 3021–3031.
Rettig GR, Behlke MA. (2012) Progress towards in vivo use of siRNAs - II. Mol Ther, 20 : 483–512.
Lundberg P, Yang H-J, Jung S-J, Behlke MA, Rose SD, Cantin EM. (2012) Protection against TNFα-dependent liver toxicity by intraperitoneal liposome delivered DsiRNA targeting TNFα in vivo. J Control Release, 160 : 194-199.
Thiel WH, Bair T, Peek AS, Liu X, Dassie J, Stockdale KR, Behlke MA, Miller FJ, Giangrande PH. . (2012) Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection. PLoS One, 7 : e43836.
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